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Treatment of Orthostatic Hypotension in SCI

RecruitingPhase 4Ages 18 Years - 60 YearsAllJames J. Peters Veterans Affairs Medical Center
NCT05839652 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.

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📋 Eligibility rules (as published)
Inclusion Criteria: * traumatic spinal cord injury * at least 12 months post injury * injury level of C1-T6 * AIS A, B or C * non-ambulatory * non-ventilator Exclusion Criteria: * Active psychiatric disorder * Stroke or cerebrovascular disease * Alzheimer's Disease or dementia * Unmanaged cardiac arrhythmias * Concurrent systemic, hepatic, or renal disease * Suspected or diagnosed malignancy * Neurological disease other than SCI * Self-reported history of three or more symptomatic episodes of AD per day
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What it tests

  • Midodrine Hydrochloride
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Where

2 sites
Kessler Foundation
West Orange, United States
James J Peters VA Medical Center
The Bronx, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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