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RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain

RecruitingNAAges 18 Years - anyAllLondon Health Sciences Centre Research Institute …
NCT05840354 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chronic spinal pain (CSP) is one of the most common chronic pain conditions globally. Steroid joint injections (SJI) are a routine treatment option for patients with CLBP that is recalcitrant to other treatments. However, SJI has been shown to have limited long-term efficacy with patients often requiring another injection within months to adequately control pain. One option to prolong the analgesic effects of SJI is to use a type of noninvasive brain stimulation called repetitive transcranial magnetic stimulation (rTMS). Previous studies have shown rTMS may be capable of providing long-term pain relief in patients with chronic back pain. However, the literature on rTMS in patients with CSP is limited and no study has explored rTMS in patients receiving recurrent SJI for pain control. In this pilot randomized controlled trial study, we'll be investigating if combining rTMS with SJI in CS

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📋 Eligibility rules (as published)
Inclusion Criteria: * Currently receiving recurrent steroid joint injections for control of chronic spinal pain at the St. Joseph's Health Centre Pain Clinic in London, Ontario, Canada, * Have pain in the spinal region of an intensity ≥4 out of 10 in the week before your most recent steroid joint injection, * Have received at least 2 steroid joint injections within the last 12 months at regular intervals * Have had a consistent medication regimen for the past 3 months. Exclusion Criteria: * Unable to read, understand, and speak English and are not able to give consent * Known or suspected serious spinal pathology (tumour, fracture, dislocation, scoliosis) * Spinal surgery in the past 12 months * History of uncontrolled mental health condition(s) * Meet any specific rTMS-related exclusion criteria listed on the safety screening questionnaire (S1; Rossi et al., 2008).
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What it tests

  • Magstim Rapid2
  • Placebo D70mm Air Film Coil
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Where

2 sites
St. Joseph's Health Care London
London, Canada
Parkwood Institute (Main Building)
London, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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