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Coronary Flow During Rapid Heart Rates

Recruitingn/aAges 18 Years - anyAllImperial College London
NCT05841199 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn about the factors which determine how well ventricular tachycardia (VT) is tolerated. The main questions it aims to answer are: 1. What impact does coronary artery disease have on the ability for a patient to tolerate VT? 2. Does treatment of coronary artery disease with stents improve the tolerability of VT? Participants who are undergoing a clinically indicated coronary angiogram or coronary angioplasty procedure will have measurements of blood pressure, coronary pressure and coronary flow made during pacing at a range of heart rates.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Able to give valid consent * Referred for coronary angiography or coronary angioplasty * Suitable for percutaneous physiological interrogation and PCI when clinically indicated Exclusion Criteria: * Unable to give valid consent * Pregnant or breastfeeding women * Unstable coronary artery disease (acute coronary syndrome) * Severe multivessel coronary artery disease suitable for coronary artery bypass grafting * Severe heart valve disease * Severe (NYHA IV) heart failure
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What it tests

  • Pressure and flow measurement during simulated VT
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Where

1 site
Imperial College NHS Foundation Trust
London, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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