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โ† Trials
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Multicentre Implementation and Validation of a Molecular Diagnostic for VitreoRetinal Lymphoma

Recruitingn/aAges 18 Years - anyAllVinodh Kakkassery, MD
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to gain new insights into the changes in proteins, genes and other molecular biological substances in the aqueous humour, vitreous humour, blood serum and, in rare cases, retina/choroid samples in patients with ocular lymphoma disease. The hope is that this will expand the understanding of the mechanisms of the disease and thus contribute to improved and simplified diagnosis and treatment strategies in the future. The aim is the inclusion of at least 220 patients during the study period. The main questions it aims to answer are: * to evaluate the diagnostic quality of extended molecular diagnostics (based on standard work-up) of vitreous samples for the specific VitreoRetinalLymphoma (a type of ocular lymphoma disease) diagnosis in comparison to standard work-up alone. * To monitor VRL patients as part of regular tumour follow-up over a period of

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Clinical suspicion of the presence of VRL with indication for diagnostic vitrectomy. Clinical suspicion is based on the assessment of the treating physicians in the clinics participating in this study. * Age over 18 years. * Written informed consent to participate in the study. Exclusion Criteria: * Systemic chemotherapy for lymphoma within 3 months prior to vitrectomy. * Cortisone use within 2 weeks before vitrectomy, macular oedema, posterior synechiae, rubeosis iridis
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What it tests

  • Not listed
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Where

1 site
University Clinic of Schleswig-Holstein
Lรผbeck, Germany
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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