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Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements

Recruitingn/aAges 18 Years - anyAllCentre Hospitalier Universitaire de la Réunion
NCT05843214 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring with the aim, among others, of detecting episodes of intracranial hypertension, each method allowing the study of one of the different pathophysiological mechanisms of its impact. However, at present there is no data in the literature on the value of these non-invasive neuromonitoring tools in the management of patients undergoing controlled intracranial surgery. The study aims to help the early detection of postoperative neurological deterioration.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Regulated intracranial surgery: scheduled \> 48 hours * French-speaking patient * No opposition from the patient or a relative when the patient is unable to consent Exclusion Criteria: * Chronic subdural haematoma * Isolated cerebral endovascular procedure * Stereotactic biopsy * Scheduled ventriculoperitoneal shunt or isolated ventriculocisternostomy * Specific non-inclusion criteria for quantitative pupillometry: known pupillary abnormalities, glaucoma, cataract surgery and any ocular surgery.
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What it tests

  • Non-invasive neuromonitoring evaluation (transcranial doppler, optic nerve envelope diameter and quantitative pupillometry)
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Where

1 site
CHU de la Réunion
Saint-Pierre, Reunion
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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