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Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial

RecruitingNAAges 18 Years - anyAll59th Medical Wing
NCT05844384 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized, single-masked, crossover, non-inferiority trial aims to evaluate the safety and efficacy of Nanodropper-mediated microdrops of ocular hypotensive topical treatments (experimental intervention) compared to standard drops of the same medication(s) (active comparator) in Wilford Hall Ambulatory Surgical Center (WHASC) primary open-angle glaucoma (POAG) and ocular hypertension (OHTN) patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * POAG/OHTN patients above the age of 18 years. * On a maximum of 2 IOP lowering medications. * Stable disease without progression in IOP, optic disc cupping, RNFL changes, and visual field changes within the previous 1 year. Exclusion Criteria: * Glaucoma not of the POAG or OHTN variety or other retinal diseases. * Progression of disease within the preceding 1 year (IOP elevation, optic disc cupping, visual field changes). * Using more than 2 IOP-lowering medications. * IOP-lowering surgical interventions or lasers except for SLT. SLT may have been completed 6+ months prior to study start date.
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What it tests

  • Nanodropper
  • Regular dropper
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Where

1 site
Wilford Hall Ambulatory Surgical Center
Lackland Air Force Base, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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