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Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis

Recruitingn/aAges 18 Years - anyAllUniversity of Manitoba
NCT05847634 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Investigation of the feasibility of monitoring processed transcutaneous electroencephalography (EEG), a method of interpreting brain activity, and near-infrared spectroscopy (NIRS), a method of determining levels of tissue oxygenation (StO2) in the brain, for patients with acute respiratory distress syndrome (ARDS) in the ICU.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patient admitted to the ICU * ARDS confirmed according to the Berlin Definition * Invasive mechanical ventilation * Deep sedation and/or neuromuscular blockade required for ARDS treatment at the discretion of the treating medical team * Application of monitoring devices feasible Exclusion Criteria: * More than 24 hours elapsed since ICU admission * Death is deemed imminent and inevitable during the next 24 hours * Known allergy to a textile component of the device * Consent declined from patient or authorized third party * The treating clinician believes that participation in the study would not be in the best interest of the patient
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What it tests

  • Masimo O3 NIRS cerebral oximetry and SedLine processed EEG
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Where

1 site
Health Sciences Centre Winnipeg
Winnipeg, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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