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Study on the Mechanism of Eating Disorder

Recruitingn/aAges 13 Years - 35 YearsAllPeking University
NCT05862389 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Eating disorders (EDs) are severe chronic psychiatric disorders with a not fully understood etiopathogenesis. Previous studies have revealed some biological mechanisms of EDs. However, the etiology and maintenance mechanism of EDs, especially the neuro-mechanisms is still unknown. To explore the pathogenic mechanism and treatment biomarkers of EDs, we design this study. the multidimensional data including the clinicopathological features, neuroimaging data (functional and structural magnetic resonance imaging), electroencephalogram and inflammatory cytokines will be used to investigate the biomarkers for diagnosis and treatment effectiveness.

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📋 Eligibility rules (as published)
Inclusion Criteria: Anorexia nervosa 1. Anorexia nervosa according to Diagnostic and Statistical Manual of Mental Disorders (5th edition) (DSM-5); 2. Age: 13-35 (including 13 and 35) 3. BMI: 13-17.5kg/m\^2 4. The participants and/or their legal guardians ( for participants who are younger than 18-year-old) sign the informed consent form voluntarily and agree to participate in all visits and examinations as required by the trial protocol. 5. Do not take any psychiatric medications in past one month. Bulimia nervosa 1. Bulimia nervosa according to Diagnostic and Statistical Manual of Mental Disorders (5th edition) (DSM-5); 2. Age: 13-35 years old (including 13 and 35) 3. The participants and/or their legal guardians ( for participants who are younger than 18-year-old) sign the informed consent form voluntarily and agree to participate in all visits and examinations as required by the trial protocol. 4. Do not take any psychiatric medications in past one month. Exclusion Criteria: 1. Patients who meet DSM-5 diagnostic criteria for other mental disorders: Major depressive disorder, anxiety, obsessive-compulsive disorder, personality disorder, mental retardation; drug and/or alcohol dependence; 2. Patients who receive repetitive Transcranial Magnetic Stimulation (rTMS) or modified electroconvulsive therapy (MECT) treatment in past six months. 3. Patients with severe suicidal tendencies or suicidal behavior 4. Pregnant or lactating women; 5. Patients with MRI contraindications; 6. Patients who are regarded as unsuitable by investigators for this clinical trial.
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What it tests

  • Not listed
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Where

1 site
Institute of Mental Health, Peking University Sixth Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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