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Value of Screening MRI Brain in Stage IV Non-small Cell Lung Cancer

RecruitingNAAges 18 Years - anyAllUniversity Medical Center Groningen
NCT05864794 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients with newly diagnosed stage IV non-oncogene addicted NSCLC, who are fit for systemic treatment and don't have any symptoms of brain disease will undergo an MRI of the brain to screen for brain disease.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Histologically or cytologically confirmed stage IV metastatic NSCLC, not amenable to curative treatment. * Fit for systemic treatment (PS 0-2) according to standard of care. * No symptoms of brain disease disease assessed according to standard clinical care by the thoracic oncologist. Exclusion Criteria: * Prior/concomitant therapy for stage IV disease. * Oncogenic diver mutation (e.g. EGFR, ALK, ROS1, RET, MET, and BRAF) with approved targeted treatment. * Contraindications for MRI scan with contrast as per standard of care protocol of the institution.
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What it tests

  • MRI
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Where

3 sites
University Medical Center Groningen
Groningen, Netherlands
Maastricht UMC+
Maastricht, Netherlands
Ommelander Ziekenhuisgroep
Scheemda, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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