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Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)

Recruitingn/aAges 50 Years - anyAllUniversity of Pennsylvania
NCT05865054 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes. The target population includes patient with suspected giant cell arteritis (GCA; temporal arteritis).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 50 years or older * First presentation of suspected GCA * New or worsening cranial manifestations within 4 weeks of enrollment concerning for active GCA * Elevated CRP greater than 1.0 mg/dl * Plan to undergo temporal artery biopsy or ultrasound for diagnosis Exclusion Criteria: * Contra-indication to receiving MRI including: Implanted medical devices, pacemaker, and metallic foreign fragments inside body/orbits Known gadolinium allergy Women who are pregnant or nursing * Absence of cranial symptoms related to GCA (e.g., only large vessel GCA)
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What it tests

  • Magnetic Resonance Imaging (MRI)
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Where

4 sites
Mayo Building and Gonda Building
Rochester, United States
3400 Civic Center Blvd
Philadelphia, United States
St. Joseph's Healthcare Hamilton
Hamilton, Canada
University Hospital Wuerzburg
Würzburg, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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