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Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes

Recruitingn/aAges 6 Years - 15 YearsAllUniversity Hospital, Angers
NCT05885646 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The effect of sulthiame on EEG has been studied in epilepsy syndromes of childhood with sleep activation by comparing sleep EEG obtained at baseline and after 4 weeks of treatment. The aim of the study is to know if an effect is still identifiable after 2 weeks of treatment by performing sleep EEG recordings after 2 and 4 weeks of treatment, respectively.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of epilepsy syndromes of childhood with sleep activation * Failure of at least two anti-epileptic drugs (AED) * Sleep EEG performed in the last 7 days before inclusion and showing interictal epileptiform discharges (baseline EEG) Exclusion Criteria: * Previous trial with sulthiame * More than 2 AED at inclusion * Use of corticosteroids at inclusion * Change in the anti-epileptic treatment in the 7 days before baseline EEG
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What it tests

  • Sulthiame
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Where

3 sites
Angers University Hospital, Pediatric department
Angers, France
Strasbourg University Hospital, Pediatric department
Strasbourg, France
Toulouse University Hospital, Pediatric Neurology Department
Toulouse, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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