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Diagnostic Performance of the Mitral Annulus Velocity Variation Measured by Tissue Doppler to Evaluate the Fluid Responsiveness During the Initial Management of Shock in Patients Admitted to the Emergency Department

Recruitingn/aAges 18 Years - anyAllCentre Hospitalier Universitaire de Nīmes
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In plain words

What the trial is, and whether it could suit you

Assessing the response to vascular filling in shock is a challenge in emergency medicine. The mitral annulus velocity measured by tissue Doppler (E') has recently been characterized as sensitive to the preload conditions of a patient. The investigators hypothesize that the E' variation (∆E') before and after fluid filling allows us to assess the response to vascular filling. The investigators hypothesize that the ∆E' has a good diagnostic performance to establish whether a patient is responsive to fluid filling, defined by an area under the ROC curve greater than 0.75.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient has been informed of the study and does not refuse to participate. * Patient is at least ≥ 18 years of age. * The patient must be beneficiary of a health insurance plan. * Patient has shock with a mean blood pressure less than 65 mmHg (\<) * The patient does not have acute intracranial pathology * The referring physician has decided on a vascular filling with 500mL of crystalloids (NaCl 0.9% or Ringer lactate) Exclusion Criteria: * The patient has already received 2 vascular fillings since the beginning of his management * The patient is in shock and has a contraindication to vascular filling : shock of a cardiogenic or obstructive nature * The patient has an intracranial pathology requiring maintain a MAP ≥ 80 mmHg * The patient is intubated or on Non-Invasive Ventilation before the vascular filling * The patient is under court protection * The patient is pregnant, parturient or nursing
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What it tests

  • Cardiac ultrasonography
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Where

1 site
CHU de Nîmes
Nîmes, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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