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Engineering Immune Organoids to Study Pediatric Cancer

RecruitingNAAges any - 25 YearsAllGustave Roussy, Cancer Campus, Grand Paris
NCT05890781 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To engineer immune organoids from pediatric patient tissues using induced-pluripotent stem cells (iPSC)

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age at diagnosis ≤ 25 years except for patients with malignant gliomas and renal tumors for whom no upper age limit is applied * Medical suspicion or diagnosis of one of the following diseases, regardless of stage: * Brain tumors * Renal tumors * Neuroblastoma * Sarcomas * Adult patient or parents or guardians should understand, sign and date the appropriate written informed consent from prior to any protocol-specific procedures performed. Patient should be able and willing to comply with study visits and procedures as per protocol. * Affiliated to a social security system or beneficiary of the same. Exclusion Criteria: * Any histology not mentioned in the inclusion criteria * Adult patient or parents/guardians incapable/incapable of giving its/their consent * Patients deprived of their liberty by a judicial or administrative decision
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What it tests

  • Skin biopsy
  • Fresh tumor sample
  • Blood sample
  • Healthy tissue from the tumor
  • Spinal cerebrospinal fluid (SCF)
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Where

2 sites
Gustave Roussy
Villejuif, France
Hopital Necker
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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