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Brain PERfusion Evaluation by Contrast-Enhanced UltraSound

Recruitingn/aAges 18 Years - anyAllAssistance Publique - Hôpitaux de Paris
NCT05893407 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objective of the study is to assess brain tissue perfusion by contrast-enhanced ultrasound perfusion imaging (PerCEUS) in acute brain injuries. More precisely, it aims : * to evaluate the heterogeneity of brain perfusion and thus diagnose brain tissue hypoperfusion with contrast-enhanced ultrasound. * to correlate contrast-enhanced ultrasound with perfusion measurements by usual multimodal monitoring.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 * Intensive care unit admission for acute brain injury * Proven acute brain injury by CT and/or MRI * Requiring a contrast ultrasound imaging * Informed consent of patient or relative Exclusion Criteria: * Pregnancy * Not sufficient temporal window * Contraindications to Sonovue ® : acute coronary syndromes, severe ischemic heart disease (requiring revascularization), pulmonary arterial hypertension \> 90 mmHg, right-left shunt, ARDS, dobutamine's use, known allergy or adverse reaction to Sonovue® * Patient on State Medical Assistance
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What it tests

  • Measuring contrast-enhanced ultrasound perfusion with phase inversion harmonic imaging
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Where

1 site
Lariboisière Hospital
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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