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A Real-world Study of Obinutuzumab-based Therapy for Previously Untreated FL

Recruitingn/aAges 18 Years - anyAllRuijin Hospital
NCT05899621 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to observe and explore the efficacy and safety of obinutuzumab-based therapy for previously untreated follicular lymphoma

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📋 Eligibility rules (as published)
Inclusion Criteria: * Pathologically confirmed CD20 positive follicular lymphoma grade 1, 2, or 3A based on 2016 WHO classification * Treatment naive * Age ≥ 18 years * Indications for treatment confirmed * Must has measurable lesion in CT or PET-CT prior to treatment * Considered suitable for GR, GB or GCHOP regimens * Informed consented Exclusion Criteria: * Transformed follicular lymphoma or 3B follicular lymphoma; * HBsAg positive and / or HBcAb positive with HBV DNA titer; HCV antibody positive with HCV-RNA; or HIV positive * Central nervous system or meninges involved * Any drug contraindication in the treatment plan * Patients judged by other researchers to be unsuitable for inclusion in the study
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What it tests

  • Obinutuzumab
  • Lenalidomide
  • Bendamustine
  • Cyclophosphamide
  • Doxorubicin
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Where

1 site
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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