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The Impact of a Race-Based Stress Reduction Intervention

RecruitingNAAges 50 Years - 75 YearsFemaleLoyola University
NCT05902741 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammation, and the epigenome in African American (AA) women who have risk factors for heart or metabolic disease. The main question it aims to answer is whether an intervention that integrates cognitive-behavioral strategies focused on the impact that social stress, such as racism, has on the body, racial identity development, and empowerment. Participants will placed in one of the two following groups: * The RiSE program will focus on teaching participants how to reduce their stress levels and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks. * The Health Education program will include education on how to improve general health and will meet online weekly for approximately 2 hours each week for 8 cons

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📋 Eligibility rules (as published)
Inclusion Criteria: * Between the ages of 50 and 75 * Female * Post-menopausal (without menstrual period for at least 12 consecutive months) * Self-identified AA or Black * Able to write, read, speak English * Must have at least 1 of any of the following: * Waist circumference \>88 cm * Systolic BP\>130 mmHg and/ or diastolic BP\>88 mmHg or on antihypertensive medications * Diagnosed and/or being treated for hypercholesterolemia * History of Type 2 diabetes Exclusion Criteria: * History of myocardial infarction or ischemic heart disease/angina, stent placement, coronary artery bypass, left ventricular hypertrophy, congestive heart failure, or ischemic stroke * Any major immune-related disease (e.g., rheumatoid arthritis. lupus) * Use of immune-altering medications, such as glucocorticoids * Periodontal disease, bleeding gums, dental work in past 72 hours * Current smoker or has smoked in past 3 months * Active cancer * Active infection * Substance abuse * Cognitive or psychiatric disorder that would affect ability to participate in classes (Brief Screen for Cognitive Impairment total score of 8 or higher)
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What it tests

  • RiSE
  • HEP
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Where

1 site
Loyola University Chicago
Maywood, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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