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Minimally Invasive Esophagectomy Pain Control Trial

RecruitingPhase 1, Phase 2Ages 18 Years - anyAllSwedish Medical Center
NCT05906134 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A pilot randomized controlled trial comparing intercostal nerve blocks, cryo-ablation plus intercostal nerve blocks, and serratus plane catheter plus intercostal nerve blocks in patients undergoing esophagectomies with minimally invasive thoracic approaches.

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📋 Eligibility rules (as published)
Inclusion Criteria: All adult individuals who undergo an esophagectomy with an intended minimally invasive approach of the chest at Swedish Medical Center-First Hill. These approaches include: * 3-hole with R video-assisted thoracoscopic surgery (VATS) * Ivor Lewis R VATS Exclusion Criteria: * Age \<18 * Unable to consent * Additional surgical procedures planned * Patients with previous thoracic surgery * Patient with chronic pain on a daily regimen of narcotics * Non-English speaking * Contraindications to neuraxial anesthesia (ongoing anticoagulation, anticipated post-operative therapeutic anticoagulation, spinal cord stimulators, anatomic abnormalities preventing epidural placement)
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What it tests

  • Local intercostal nerve block
  • Cryo-analgesia and intercostal nerve block
  • Serratus plane catheter blocks and intercostal nerve blocks
  • Thoracic epidural catheter
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Where

1 site
Swedish Cancer Institute
Seattle, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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