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Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis

RecruitingNAAges any - anyAllUniversity of Catania
NCT05906810 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with peri-implantitis/peri-implant mucositis and without any cardiovascular disease.

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📋 Eligibility rules (as published)
PERI-IMPLANTITIS GROUP Inclusion Criteria: • Clinically diagnosed with peri-implantitis according to the EFP/AAP 2017 criteria. Exclusion Criteria: * Periodontal treatment, implant surgery, antibiotics, NSAIDs, immunosuppressants during the last 6 months. * Pregnancy. * Cardiovascular Diseases. PERI-IMPLANT MUCOSITIS GROUP Inclusion Criteria: • Clinically diagnosed with peri-implant mucositis according to the EFP/AAP 2017 criteria. Exclusion Criteria: * Periodontal treatment, implant surgery, antibiotics, NSAIDs, immunosuppressants during the last 6 months. * Pregnancy. * Cardiovascular Diseases. HEALTHY GROUP Inclusion Criteria: • Clinically diagnosed with healthy periodontum withouth periodontitis history according to the EFP/AAP 2017 criteria. Exclusion Criteria: * Scaling, antibiotics, NSAIDs, immunosuppressants during the last 6 months. * Pregnancy. * Cardiovascular Diseases.
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What it tests

  • Non-surgical periodontal treatment
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Where

1 site
AOU Policlinico G. Rodolico
Catania, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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