🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

MR-Only Based Adaptive External Beam Radiation Therapy of Cervical Cancer on Ethos Therapy: Feasibility Study

RecruitingNAAges 18 Years - anyFemaleRecherche clinique
NCT05909111 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Current management of patients treated with External Beam Radiation Therapy (EBRT) for cervical cancer with a classical Image-guided Radiation Therapy (IGRT) strategy involves a complex, not entirely satisfactory, treatment workflow. Indeed, in our institution, two workflows have been designed to take into account the inter-fraction motion of cervix and uterus : an Internal Target Volume (ITV)-based approach and a plan of the day strategy requiring both several planning-CT (Computed Tomography) acquisitions with variable bladder filling.The upcoming installation of a Varian Ethos therapy system in our institution will allow us to implement a less cumbersome online adaptive radiotherapy strategy (oART), which, by conforming to the daily anatomy, will enable a reduction in the Clinical Target Volume (CTV) to Planning Target Volume (PTV) margins leading to an expected reduction in dose deli

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age \> 18 years old * Histologically proven cervical cancer (SCC, ADK ou adenous-SCC) * Patient for curative RTCT treatment * FIGO/TNM Stage IB2, IIA, IIB, IIIA, IIIB with or without lymph nodes involvement * WHO \< 2 * No pregnancy * Informed consent dated and signed * Patient affiliated or beneficiary of a social security scheme * Free, informed and written consent signed by the participant and the investigator (at the latest on the day of inclusion and before any examination required by the research). Exclusion Criteria: * Metastatic disease * Contraindications to IRM examinations (claustrophobia, presence of metallic elements..) * Signes of active infection or serious health problems * Historic of abdominal or pelvis RT * Surgical history: partial or total hysterectomy
💊

What it tests

  • Magnetic resonance imaging
📍

Where

1 site
Institut Sainte Catherine
Avignon, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy