🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

NC Testing in LC & POTS

RecruitingNAAges 18 Years - 60 YearsAllUniversity of Calgary
NCT05914649 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Patients with Postural Orthostatic Tachycardia Syndrome (POTS) and Post-Acute Sequelae of COVID (PASC, or "Long COVID") experience cognitive dysfunction. The investigators will test the hypothesis that 999 mL of IV saline will improve cognitive function in patients with POTS and Long COVID compared to placebo (50 mL of saline).

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with diagnosis of Long COVID * SARS-COV2 test positive * Symptoms \> 12 weeks post COVID * Subjective complaint of 'brain fog" or cognitive dysfunction * Patients with diagnosis of Postural Orthostatic Syndrome (POTS) from the Calgary Autonomic Investigation and Management Clinic * Subjective complaint of 'brain fog" or cognitive impairment * Healthy participants * Without POTS or "brain fog" * Age 18 to 60 years * Female and Male * Able to give an informed consent Exclusion Criteria: * Patients with overt causes for POTS (e.g., dehydration, prolonged bed rest) * An inability to safely withdraw from medicine(s) that could make test interpretation difficult and impossible. * Other factors which are in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies or an unpredictable schedule. * Unable to give an informed consent.
💊

What it tests

  • IV normal saline (999 mL infusion)
  • IV normal saline (50 mL infusion)
📍

Where

1 site
University of Calgary
Calgary, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy