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Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted to Intensive Care for Septic Shock.

Recruitingn/aAges 18 Years - 65 YearsAllCentre Hospitalier de Lens
NCT05928767 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of the study is to demonstrate that "frail" patients, defined as having a CFS score greater than or equal to 5, and "severely" frail patients, defined as having a CFS score between \[6-7\] as defined by Bagshaw et al (14), constitute an independent risk factor (RF) for mortality. In the same way, as an exploratory study, we will try to find out whether clinical frailty constitutes a risk factor for extending the length of hospital stay, the risk of short/medium-term readmission, as has already been demonstrated for patients admitted to intensive care from all causes (15), or for impaired quality of life. The objective is to have a better understanding of the implications and outcomes associated with pre-hospital frailty in young critically ill patients. This analysis will also help to clarify prognoses and contribute to better decision-making on the intensity and proportionali

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged ≥18 years and ≤ 65 years * Patient admitted to intensive care - resuscitation * Patient admitted for suspected or documented type 3 sepsis * Presence of vasopressor amines to maintain MAP \> 65mmHg despite filling * Lactatemia ≥ 2 mmol/L on admission. Exclusion Criteria: * Patient moribund on admission * Patients with severe pre-existing dementia and/or cognitive decline, suffering from severe neurodegenerative diseases that prevent the patient from living independently at baseline, including mental illness requiring institutionalisation, including acquired or congenital mental retardation, etc. * Pregnant women or women in labour * Patients under guardianship or curatorship * Patients deprived of their liberty * Patient and/or family unable to speak or understand French.
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What it tests

  • Not listed
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Where

5 sites
Ch Germon Et Gauthier
Béthune, France
CH Boulogne sur Mer
Boulogne-sur-Mer, France
CHU de Dijon
Dijon, France
CH de Lens
Lens, France
CHU Lille
Lille, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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