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Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection

RecruitingPhase 3Ages 18 Years - 85 YearsAllBlokhin's Russian Cancer Research Center
NCT05939687 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare the efficacy of using polypropylene mesh for hernia prevention after stoma closure in patients with colorectal cancer and non-mesh repair. The main question it aims to answer is: can mesh help prevent hernia? Participants will be divided into 2 groups: with and without mesh using. They must be followed up for 2 years after enrollment in the study. Researchers will compare mesh and non-mesh groups to evaluate the benefits and harms of mesh using in hernia prevention.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Signed informed consent * Absence of distant metastases (M0) * ECOG (Eastern Cooperative Oncology Group) status 0-2 * completed course of adjuvant treatment * Absence of acute inflammatory parastomal complications * Integrity of colorectal anastomosis Exclusion Criteria: * Inability to obtain consent to participate * Synchronous and metachronous malignant neoplasms * Clinically significant diseases of the cardiovascular system, liver, kidney, central nervous system * Parastomal inflammation and other conditions that increase the risk of postoperative complications * Pregnancy * HIV infection
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What it tests

  • mesh
  • non-mesh
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Where

1 site
N.N.Blokhin Russian Cancer Research Center
Moscow, Russia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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