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Swiss 2024 Continous Fever Monitoring in Pediatric Oncology Patients

RecruitingNAAges 1 Month - 17 YearsAllInsel Gruppe AG, University Hospital Bern
NCT05940766 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In children and adolescents undergoing chemotherapy for cancer, fever in neutropenia (FN) is the most frequent potentially lethal complication of chemotherapy for cancer. Emergency hospitalization and empirical treatment with i.v. broad-spectrum antibiotics have reduced lethality from \>50% in certain high risk situations to \<1%. Fever without neutropenia is a further complication requiring emergency evaluation and often emergency treatment. Continuous monitoring of fever leads to earlier fever detection compared to the usual discrete fever measurements performed only for clinical reasons. Earlier detection of fever leads to earlier assessment and treatment and thus can reduce the risk of complications. This study primarily aims to assess, in pediatric patients undergoing chemotherapy for cancer, the efficacy of automated fever alerts resulting from continuous fever monitoring (CFM) u

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📋 Eligibility rules (as published)
Inclusion Criteria: * Chemotherapy treatment because of any malignancy expected to last ≥2 months at time of recruitment for myelosuppressive therapy, or at least 1 cycle of myeloablative chemotherapy followed by hematopoietic stem cell transplantation * Age ≥1 month and \<18 years at time of recruitment * Written informed consent from patients and/or parents Exclusion Criteria: * Neonates \<1 months * Local skin disease prohibiting wearing of the WD * Denied written informed consent from patients and/or parents * Inclusion of vulnerable participants mandatory as vital signs and FN episodes differ significantly in children and adults
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What it tests

  • Automated fever alerts
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Where

1 site
Childrens' Clinc Bern, Inselspital Bern
Bern, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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