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Impulsivity With Borderline Personality Disorder/tMS

RecruitingNAAges 18 Years - anyAllHôpital le Vinatier
NCT05942651 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a prospective, randomized, double-blind, parallel-group controlled trial. The aim of this research project is to compare the clinical benefits achieved in patients with Borderline Personality Disorder (BPD) following two types of intervention: ccPAS active or ccPAS sham.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of BPD (established by a psychiatrist and confirmed in a structured interview using the MINI) based on the Diagnostic and Statistical Manual of Mental Disorders (DSM V). Exclusion Criteria: * Contraindications to TMS/MRI (pacemakers or other devices likely to interfere with the magnetic field). * Pregnant or breast-feeding women. * Ongoing anxiolytic treatment (benzodiazepines), neuroleptic treatment or anticonvulsants acting on GABAergic transmission ; 24 hours prior to the protocol. * Diagnosis of other chronic psychiatric pathology including bipolar disorder type I or II and addictions (except tobacco). * Protective measure (curatorship or guardianship)
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What it tests

  • Non-invasive brain stimulation protocol (Cortico-cortical paired associative stimulation protocol (ccPAS)) delivered at 4 ms intervals.
  • Non-invasive brain stimulation protocol (Cortico-cortical paired associative stimulation protocol (ccPAS)) delivered at 100 ms intervals
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Where

1 site
Centre Hospitalier Le Vinatier
Bron, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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