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Quality of Life in Acute Complicated and Chronic Recurrent Left-sided Diverticulitis

RecruitingNAAges 18 Years - anyAllKepler University Hospital
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In plain words

What the trial is, and whether it could suit you

Patients presenting in hospital with symptoms of acute diverticulitis. Acute inflammation of the left-sided colon is confirmed with CT scan or ultrasound in experienced centers and diagnosis is defined according to the "Classification of Diverticular Disease (CDD)". CDD Type 2a, 2b and 3b will be included and then randomized in two groups. Group A will get an early left hemicolectomy 7 to 10 days after admission and initial antibiotic therapy and/or drainage of the abscess. Group B is designated for an elective resection 6 to 8 weeks after dismissal at the earliest and initial conservative treatment and/or after drainage of the abscess. Six weeks after the operation patients of Group A will be asked for their present quality of life with a standardized scoring system (Gastrointestinal Quality of Life Index = GIQLI; Short-form 36 Score = SF-36 Score; Low anterior resection syndrome = LARS

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Informed consent to participate in the study * CDD Type 2a, 2b: acute complicated left-sided diverticulitis * CDD Type 3b: relapsing diverticulitis without complications (\>2 episodes within 2 years) * Acute presentation * Inflammation located in the left-sided colon * Inflammation is CT proven or ultrasound confirmed from experienced radiologists Exclusion Criteria: * \< 18 years * Pregnancy * BMI \> 55kg/m2 * Current colorectal carcinoma in the left-sided colon * Oral and/or intravenous corticosteroid * Ongoing chemotherapy * Status post left hemicolectomy * Patients who cannot take care of themselves at home or are unable to follow instructions * Patients who are not fit for surgery (anesthesia, expert knowledge from specialists) and will not benefit from surgery
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What it tests

  • Sigmoid resection
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Where

4 sites
Ordensklinikum Elisabethinen Linz
Linz, Austria
Krankenhaus Barmherzige Schwestern Linz
Linz, Austria
Kepler University Hospital
Linz, Austria
Universitätsklinikum Mannheim
Mannheim, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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