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Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer

RecruitingNAAges 18 Years - 75 YearsAllSixth Affiliated Hospital, Sun Yat-sen University
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to compare the postoperative anal function of patients with ultra-low rectal cancer after Parks operation (colon anal anastomosis) and Bacon operation (colon anal pull-out anastomosis), which may provide clinical evidence for the improvement of anal function and quality of life. The main questions it aims to answer are: the difference of anal function 1 year after surgery type of study: clinical trial participant population: patients with low rectal cancer Participants will receive Parks operation of Bacon operation If there is a comparison group: Researchers will compare Parks and Bacon operation to see if the anal function 1 year after surgery is different.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Men or women, aged between 18 and 75 years; 2. Pathological diagnosis of rectal cancer before operation, with the distance from the lower edge of the tumor to the dentate line โ‰ค 3cm by MR imaging; 3. No local complications (including complete/ incomplete obstruction, active bleeding, local invasion of sphincter or levator ani, etc.) before operation; 4. Suitable for anal preservation surgery discussed by MDT; 5. Adequate bone marrow, liver, renal and cardiac function meeting the requirements of surgery and anesthesia; 6. R0 resection is expected technically; 7. Provision of written informed consent. Exclusion Criteria: 1. Previous history of malignant colorectal tumors; 2. Complications such as obstruction and gastrointestinal bleeding that need an emergency operation; 3. Unachievable R0 resection due to invasion of adjacent organs by primary tumor; 4. Multiple primary tumors; 5. History of other malignancy; 6. Participation in other clinical trials within the previous 4 weeks of enrollment; 7. ASA physical status score โ‰ฅ IV level and/or ECOG performance status โ‰ฅ 2; 8. Intolerance of surgery due to liver, renal, cardiopulmonary or coagulation dysfunction, or underlying diseases; 9. History of serious mental disorders; 10. Women in pregnancy or lactation period; 11. Uncontrolled infection before operation; 12. Unsuitable to be included due to other clinical and laboratory conditions by the judgement of investigators.
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What it tests

  • Parks technique
  • Bacon technique
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Where

1 site
The Sixth Affiliated Hospital, Sun Yatsen University
Guangzhou, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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