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Prediction Models for Cardiovascular and Neurocognitive Disease Risk in the General Population

Recruitingn/aAges 45 Years - anyAllAssistance Publique - Hôpitaux de Paris
NCT05951764 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

More accurate and earlier identification of people at risk of cardiovascular disease (CVD) and neurodegenerative diseases (memory, cognition, dementia) through the appropriate use of biomarkers could lead to earlier initiation of preventive therapies and potentially avoid sometimes fatal events and complications. Biomarkers are useful for determining the risk of disease, but also for establishing a diagnosis. High inter-individual variability hinders the establishment of general laws that can be- used in predictive medicine. In addition to the lack of validation, other limitations are the low participation rate in screening campaigns (regardless of disease) and the relative difficulty, accuracy, cost and time taken to perform the measurements. The perioperative period is a very good time to screen for cardiovascular and neurodegenerative pathologies for several reasons: * Patients c

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients \> 45 years old * Eligible for outpatient or scheduled surgery or interventional procedures under general anesthesia or locoregional anesthesia with sedation. * Patient having expressed no objection to participation in this research. * Patient who is not subject to a legal protection measure Exclusion Criteria: * Patients under 45 years of age. * Patient opposed to participation in the protocol * Pregnant woman * Patient under judicial protection * Patient not affiliated to a social health system
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What it tests

  • Non-invasive measurement of arterial stiffness by Pulse Wave Velocity (PWV)
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Where

1 site
AP-HP, Lariboisière Hospital, Department of Anesthesiology and Intensive Care
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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