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Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Controlled Trial

RecruitingNAAges 65 Years - 80 YearsAllIstituti Clinici Scientifici Maugeri SpA
NCT05954741 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Dementias secondary to cerebrovascular diseases are of significant epidemiological and clinical relevance. As a result, the management of individuals with comorbid dementia should involve early diagnosis, effective treatment, and patient-centered care planning, both in specialist and in non-specialist settings. It is well known that physical exercise can improve various aspects of health, including resistance, balance, strength, and cognitive functions such as attention and executive performance. However, the efficacy of cognitive rehabilitation is still not definitive and requires further clarification. Preliminary evidence suggests that a combination of cognitive and motor training along with novel technological approaches has the potential to maintain or improve compromised cognitive function more effectively compared to a single intervention. A multidomain intervention could enhance

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age Between 65 and 80 years. * Neurocognitive Disorder due to vascular disease with Clinical Dementia Rating Scale score between 0.5 and 1, symptoms onset \< 12 months. * Neurocognitive Disorder due to multiple etiology with Clinical Dementia Rating Scale score between 0.5 and 1, symptoms onset \< 12 months. Exclusion Criteria: * Other known neurological conditions involving cognitive functioning (e.g. Parkinson's disease, Multiple Sclerosis, head trauma, alcohol abuse). * Severe organic instability. * Neoplasia in progress. * Severe psychiatric condition. * Illiteracy. * Severe perception deficits. * Severe motor disability. * Specific intellectual deficit. * Participation in other forms of training or neurostimulation in the previous 6 months. * Pharmacological interventions of neurological pertinence in the month before the study.
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What it tests

  • Motor rehabilitation alone
  • Motor rehabilitation and Cognitive rehabilitation (paper-based)
  • Motor rehabilitation and cognitive rehabilitation (digital-based)
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Where

1 site
ICS Maugeri - Montescano
Montescano, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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