🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery

RecruitingPhase 3Ages 18 Years - 90 YearsAllRabin Medical Center
NCT05959603 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Cefazolin is given routinely pre and intraoperatively for patients undergoing spinal surgery to reduce the rate of infection. Intra-wound admission of Vancomycin powder has been suggested to reduce wound infection rates. Therefore, this study aims to compare the rate of wound-related complications between patients receiving standard treatment compared to patients receiving an addition of topical Vancomycin and to identify the optimal Vancomycin dosage. All groups will receive the recommended regimen of routine IV antibiotic prophylaxis.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Patients undergoing posterior spinal fusion operation at the neurosurgery department at the Rabin Medical Center * Ability to understand and sign written informed consent by the patient or legal guardian Exclusion Criteria: * Preoperative ongoing infectious disease present as judged by the primary surgeon (based on lab results and clinical assessment) * Receiving ongoing treatment of antibiotics for other infections * Sensitivity or allergy to vancomycin or cefazolin * Previous spine surgery at the index level within the last 90 days * Postoperative radiotherapy of the surgical site required (e.g. for tumor) * Renal insufficiency with stage 4 chronic kidney disease (CKD) with a glomerular filtration rate (GFR) of 15-30 ml/min or worse * Undergoing spinal decompression only * Trauma patients * Pregnancy
💊

What it tests

  • Vancomycin
📍

Where

1 site
Rabin Medical Center
Petah Tikva, Israel
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy