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Change in Inflammatory State in Patients Undergoing Transcatheter Ablation of Atrial Fibrillation

Recruitingn/aAges 18 Years - 85 YearsAllFondazione IRCCS Ca' Granda, Ospedale Maggiore Po…
NCT05961865 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

It is a non-pharmacological (biological), spontaneous observational study. The main objective is to evaluate the correlation between inflammation markers and local adiposity, clinical risk factors and their possible variation following an AF ablation procedure

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📋 Eligibility rules (as published)
Inclusion Criteria: * Paroxysmal or persistent AF; * Patients undergoing ESC/ERAH(European Society of Cardiology/European Heart Rhythm Association) approved catheter ablation procedures; * Aged between 18 and 85 years; * Ability to provide informed consent for study participation. Exclusion Criteria: * Age \> 85 years or \< 18 years; * Presence of left auricular thrombosis on pre-procedural transesophageal echocardiogram; * NYHA functional class IV; * Left ventricular ejection fraction \<30%; * Myocardial infarction or unstable angina or recent coronary artery bypass graft (\<6 months); * Significant co-morbidity, such as cancer, severe renal failure requiring dialysis, severe obstructive pulmonary disease, cirrhosis, with a life expectancy of less than 12 months; * Presence of contraindications to the procedure; * Inability to provide informed consent for study participation.
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What it tests

  • Markers of inflammation and fibrosis
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Where

1 site
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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