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โ† Trials
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Neural Prediction to Enhance Language

RecruitingNAAges 0 Months - 5 YearsAllAnn & Robert H Lurie Children's Hospital of Chicaโ€ฆ
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In plain words

What the trial is, and whether it could suit you

The language outcome of children receiving cochlear implantation to address bilateral sensorineural hearing loss is more variable than that of typical hearing children. The research is focused upon development of neural predictive models based upon brain imaging to forecast language after cochlear implantation on the individual child level. The long-term goal is improving children's language by using predictive models to enable a custom "predict to prescribe" approach to intervene with more effective behavioral therapy for children at risk to develop poorer language. The investigators previously developed models for short term language outcome of English-learning implanted children. The aims of this study are to 1. Develop models able to predict long term outcome for English- learning and Spanish-learning children; and 2. To evaluate whether English-learning children predicted to achieve

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria (Arm 1): 1. Children with sensorineural hearing loss who meet clinical criteria for cochlear implantation in both ears who meet the following age criteria at time cochlear implant evaluation begins: * Age 5 years and under. * English or Spanish as the dominant language. 2. English or Spanish dominant language in the home. Inclusion Criteria (Arm 2): 1. Children with bilateral sensorineural hearing loss who meet clinical criterial for cochlear implantation 2. English dominant spoken language by family 3. Age at implantation of 36 months and younger when treatment begins 4. Parent or caregiver that is willing to participate who understands spoken English 5. Child is exposed to spoken language by at least one parent (total communication or auditory/oral) in the home Exclusion Criteria (Arm 1): 1. Severe motor and /or cognitive disability that would preclude evaluation of progress 2. Limited electrode insertion likely to significantly impact development of speech perception 3. Hearing loss due to bacterial meningitis 4. Neither English or Spanish as the dominant family language in the home Exclusion Criteria (Arm 2): 1. Severe motor and /or cognitive disability that would preclude evaluation of progress 2. Limited electrode insertion likely to significantly impact development of speech perception 3. Hearing loss due to bacterial meningitis 4. Dominant language other than English 5. Diagnoses or medical conditions expected to impact language development independent of hearing loss 6. Cochlear nerve deficiency in implanted ears or severe cochlear malformation 7. Children already having spoken language who score better than 25th percentile on the Words and Sentences portion of the CDI language evaluation. 8. Child with more than two months CI experience prior to start of treatment
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What it tests

  • Parent-Implemented Communication Treatment
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Where

1 site
Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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