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Ethanol Sclerotherapy Prior to ART

RecruitingNAAges 18 Years - 40 YearsFemaleAnkara University
NCT05962775 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this randomized controlled trial is to assess the impact of ethanol sclerotherapy on ART cycle outcomes. The main questions it aims to answer are: 1. Does ethanol sclerotherapy before ART cycle has any impact on cumulative live birth rate in patients with endometrioma? 2. Does ethanol sclerotherapy improve chronic pelvic pain, dysmenorrhea, complications during oocyte retrieval, response to ovarian stimulation (number of mature oocytes retrieved), and pregnancy loss rates? Infertile patients with endometrioma between 4-10 cm who are scheduled for ART within 2 cycles will be randomized to ethanol sclerotherapy or no intervention.

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📋 Eligibility rules (as published)
Inclusion Criteria: * AMH\>0.3 ng/ml * unilateral/bilateral endometrioma * Endometrioma diameter 40-100 mm Exclusion Criteria: * 3 or more IVF/embryo transfer failure * Menstrual cycle abnormalities * Male Factor infertility * Presence of uterine fibroids * Presence of hydrosalpinx * Presence of uterine abnormalities * Suspicion of malignancy according to International Ovarian Tumor Analysis criteria
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What it tests

  • Ethanol Sclerotherapy for Endometrioma
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Where

3 sites
Başkent University Adana IVF Center
Adana, Turkey (Türkiye)
Ankara University School of Medicine, Department of Obstetrics and Gynecology
Ankara, Turkey (Türkiye)
Bahçeci IVF Clinic
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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