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Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)

Recruitingn/aAges 18 Years - anyAllSirtex Medical
NCT05967143 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This registry seeks to prospectively gather a large repository of comprehensive observational data reflecting routine use of SIR-Spheres in patients diagnosed with unresectable HCC or unresectable liver metastases from mCRC refractory to or intolerant to chemotherapy, in order to assess clinical response in a real-world setting and further validate the safe and appropriate use of SIR-Spheres

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 years or older * Confirmed diagnosis of: * Unresectable hepatocellular carcinoma (HCC) Or * Unresectable liver metastases from colorectal cancer (mCRC) refractory to or intolerant to chemotherapy * Identified as a candidate for SIR-Spheres treatment as deemed appropriate during the normal course of practice * Planned to receive SIR-Spheres treatment to the liver for the first time * Provision of signed patient informed consent Exclusion Criteria: * Prior radiation treatment to the liver Caveat: Sequential selective internal radiation therapy (SIRT) treatment is allowed * Patients participating in any interventional clinical trial with an investigational product, device, or procedure * Need for surrogate consent. Patients who are not able to consent on behalf of themselves are not eligible.
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What it tests

  • SIRT
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Where

9 sites
Hôpital Beaujon
Clichy, France
Hopital Henri Mondor
Créteil, France
Hospices Civils de Lyon HCL Centre Hospitalier Lyon-Sud
Pierre-Bénite, France
Hospital Universitario Puerta de Hierro - Majadahonda
Majadahonda, Spain
Hospital General Universitario Gregorio Marañon
Madrid, Spain
Hospital Clinico Universitario de Valencia
Valencia, Spain
The Christie Hospital
Manchester, United Kingdom
Kings College Hospital
London, United Kingdom

…and 1 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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