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Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)

RecruitingNAAges 18 Years - anyAllKarolinska Institutet
NCT05980793 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint. The main questions it aims to answer are: * Are the treatments effective? * Is the surgical treatment more effective than the non-surgical treatment? Participants will receive surgical treatment (PIP joint denervation) or non surgical treatment (patient education plus exercise). Researchers will compare the non-surgical and surgical groups to see if pain, patient-reported function, quality of life, movement and grip strength differs between the groups.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years. * Chronic symptomatic osteoarthritis in the PIP-joint. * Radiological signs of osteoarthritis on posteroanterior and lateral radiographs assessed by the Kellgren-Lawrence classification (grade II-IV) (Kellgren \& Lawrence, 1957). * Clinical signs of PIP-joint arthritis. Exclusion Criteria: * Inflammatory arthritis. * Ongoing infection in the hand. * Inability to co-operate with the follow-up protocol. * Intra-articular glucocorticoid, PRP or Hyaluronic acid injections in the affected joint less than 3 months prior to enrollment.
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What it tests

  • PIP joint denervation
  • Patient education plus exercise
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Where

1 site
Department of Hand Surgery, Södersjukhuset
Stockholm, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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