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Impact of Emotional Reactivity on Dysfunctional Decision-Making in NSSI Adolescents

Recruitingn/aAges 15 Years - 18 YearsAllUniversity of Electronic Science and Technology o…
NCT05981612 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Studies revealed that dysfunctional interpersonal relationships and reward-related decision-making may play crucial roles in this maladaptive behavior, especially in adolescents. These interpersonal decision contexts are characterized by constant updating of expectations of rewards and the actual received rewards as well as the associated emotional reactions. These processes have recently been computationally formalized as prediction errors (PE), specifically reward PEs, valence PEs, and arousal PEs (Heffner et al., 2021; Nat Hum Behav). In the current study, the investigators aim to investigate whether these PEs make discernible contributions to social decisions in the context of unfair experiences among adolescents with NSSI and matched healthy control adolescents (HC). Specific

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📋 Eligibility rules (as published)
Inclusion Criteria: * 15-18 years * right-handed * normal or corrected normal visual acuity * meet the proposed DSM-5 frequency criteria (e.g., ≥5 days of NSSI behaviors in the past year) Exclusion Criteria: * diagnosis of borderline personality disorder, major depressive disorder, other * psychiatric disorders, etc. * high suicidal risk * recent use of medications that can affect neural activity * have received or are receiving Dialectical Behavior Therapy (DBT) other treatment for emotional problems within the past 6 months * have a contraindication to MRI scanning (e.g., metal implants, claustrophobia or other conditions that make them inappropriate for MRI scanning)
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What it tests

  • Not listed
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Where

1 site
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China
Chengdu, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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