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Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

RecruitingPhase 2, Phase 3Ages 18 Years - 60 YearsAllDow University of Health Sciences
NCT05989386 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: * Incidence of SSI after intervention * Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.

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📋 Eligibility rules (as published)
Inclusion Criteria: * • Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi * The age of patients should be between 18-60 years old. Exclusion Criteria: * Diabetic patients * Immune-suppressed patients * Patients taking steroids * Patients undergoing chemo-radiotherapy. * Pregnant females * Previous abdominal surgery within the last 30 days. * Presence of concurrent abdominal wall infections. * Trauma Laparotomies * Large Bowel perforations
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What it tests

  • 0.9% saline solution
  • Povidone-iodine Swab
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Where

1 site
Dr. Ruth K. M. Pfau Civil Hospital Karachi
Karachi, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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