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Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion

RecruitingNAAges 18 Years - 80 YearsAllShengjing Hospital
NCT05990244 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. age older than 18 years 2. Karnofsky performance status higher than 60 3. with written informed consent 4. MRE performed within one week before surgery 5. tumor diameter \> 2 cm Exclusion Criteria: 1. previous treatment for glioma 2. inability to complete MRE due to intolerance (e.g., vibration-related discomfort or claustrophobia) 3. completed MRE with suboptimal wave image quality (e.g., motion artifacts or inad-equate wave amplitude) 4. failure to proceed with surgery after MRE 5. missing IDH results
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What it tests

  • Magnetic Resonance Elastography
  • Assessment and Recording
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Where

1 site
Shengjing Hospital
Shenyang, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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