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Sevoflurane General Anesthetic and Spatial Memory in Humans

Recruitingn/aAges 30 Years - 50 YearsAllUniversity of Chile
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn about the effect of general anesthetic on spatial memory in adults who will undergo to an elective surgery. The main question it aims to answer is: • A surgical event under general anesthesia with sevoflurane transiently impairs spatial memory in humans and induces an increase in inflammatory cytokines. Participants will perform a virtual maze test and plasma samples will be taken before and after surgery.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Candidate for elective laparoscopic surgery of cholecystectomy. * Age 30 to 50 years. Exclusion Criteria: * Visual or hearing difficulties. * Malignant hyperthermia. * Being treated with centrally acting drugs, such as anxiolytics, antidepressants, antipsychotics, anticonvulsants, anticholinergics, and first-generation antihistamines. * Present a disorder of the sphere of neuropsychiatry * Substance abuse disorder.
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What it tests

  • Surgery/general anesthesia
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Where

2 sites
Centro de Investigación Cínica Avanzada (CICA), Hospital Clinico de la Universidad de Chile
Santiago, Chile
Hospital Clinico de la Universidad de Chile
Santiago, Chile
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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