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Changes in Inhibition and Valuation After Eating

RecruitingNAAges 18 Years - 45 YearsFemaleIcahn School of Medicine at Mount Sinai
NCT05995496 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female * Aged 18 to 45 years * Current BMI greater than or equal to 18.5kg/m2 but under 30kg/m2 * Right-handed * English-speaking Additional Inclusion Criteria for Women with Bulimia Nervosa: * Meet DSM-5 criteria for bulimia nervosa Exclusion Criteria: * Medical instability * Ongoing medical treatment, medical condition, or psychiatric disorder that may interfere with study variables or participation * Shift work * Pregnancy, planned pregnancy, or lactation during the study period * Allergy to any of the ingredients in or unwillingness to consume the standardized meal or unwillingness to drink water during the fasting period * Any contraindication for fMRI
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What it tests

  • Fasting state
  • Fed state
  • Magnetic Resonance Imaging
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Where

1 site
Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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