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The Swiss Neurodevelopmental Outcome Registry for Children With CHD

Recruitingn/aAges 1 Week - 6 WeeksAllUniversity Children's Hospital, Zurich
NCT05996211 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Introduction: Congenital heart disease (CHD) is the most frequent birth defect. As survival has significantly improved, attention has turned to neurodevelopmental outcomes of children undergoing heart surgery in early infancy. Since multiple risk factors contribute to neurodevelopmental alterations, a nationwide registry collecting data on medical characteristics, interventions, clinical course and neurodevelopment until school-age is needed to improve the quality of management, identify risk- and protective factors affecting neurodevelopment, and facilitate multicenter trials. Methods and analysis: The Swiss Outcome Registry for CHIldren with severe congenital heart Disease (ORCHID) is a nationwide, prospective, population-based patient registry developed (1) to collect baseline characteristics and clinical data of CHD patients operated with bypass-surgery or hybrid procedures in the f

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📋 Eligibility rules (as published)
Inclusion Criteria: * Neonates (including preterm born children) with severe CHD * Requiring an invasive cardiac intervention (including heart-lung-machine) within the first 6 weeks of life. Exclusion Criteria: * Neonates (including preterm born children) with simple CHD * Requiring simple cardiac surgery or catheter intervention such as closure of patent arterial duct or simple repair of aortic coarctation without heart-lung-machine and low impact on neurodevelopmental outcome.
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What it tests

  • Not listed
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Where

3 sites
University of Bern
Bern, Switzerland
University of Lausanne
Lausanne, Switzerland
University Children's Hospital
Zurich, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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