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Post-therapeutic Imaging Evaluation of Patients With Horton's Disease (Giant Cell Arteritis) (EvHortim)

Recruitingn/aAges 50 Years - anyAllFondation Ophtalmologique Adolphe de Rothschild
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In plain words

What the trial is, and whether it could suit you

Giant cell arteritis (GCA), also known as Horton's disease, is an inflammatory arteritis of the large and medium-sized arteries, with an estimated incidence of 17.8/100,000 in people over 50. The disease presents potential ophthalmological, neurological, cardiac and aortic vascular complications, making diagnosis an emergency in cases of suspected Horton's disease. only corticosteroid therapy started as early as possible can prevent these complications. Diagnosis has historically relied on temporal artery biopsy, but the recent ACR/EULAR 2022 classification criteria propose alternatives to this invasive examination, in particular imaging tests such as temporal artery ultrasound and PET scans. Although not included in these latest recommendations, high-definition wall MRI can also provide arguments in favor of this diagnosis, and avoid the need for a temporal artery biopsy, the sensiti

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patient aged 50 and over * Having received informed consent to participate in the study * Affiliated or beneficiary of a social insurance scheme * Patients with giant cell arteritis according to ACR/EULAR 2022 criteria * Diagnosed with MRI and ultrasound. Exclusion Criteria: * Absolute or relative contraindication to MRI (incompatible implantable device, claustrophobia, etc.) * Hypersensitivity to gadobutrol * Patient under legal protection * Pregnant or breast-feeding women
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What it tests

  • Injected cerebral MRI angiography and ultrasound of the superior aortic trunks, temporal and axillary arteries
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Where

1 site
Hopital Fondation Adolphe de Rothschild
Paris, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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