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Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

RecruitingNAAges 18 Years - anyAllM.D. Anderson Cancer Center
NCT06004882 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain: * A standard steroid injection * Peripheral nerve stimulation (PNS) therapy in combination with a standard steroid injection * PNS therapy in combination with a placebo injection Steroid injections are given directly into the knee joints and are considered to be the standard therapy for chronic knee pain. In this study, the injection will be made of the steroid drugs triamcinolone and bupivacaine.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients diagnosed with chronic knee pain (baseline pain score \>=4), seen at Pain Management Center at MD Anderson Cancer Center; if patient has bilateral knee pain, the side with the more severe knee pain will be treated first and counted towards the primary and secondary endpoints * Patients between ages 18-85 years old * Patient signed informed consent Exclusion Criteria: * Patients with cognitive dysfunction or without capacity to consent * Patient with recent history (\<6 months) of drug or alcohol abuse * Patients with open skin lesion or undergoing antibiotic therapy for local for systemic infection * Patients with allergies to local anesthesia, steroids, or adhesives * Patients who are on opioids for reasons other than knee pain
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What it tests

  • PNS therapy
  • Triamcinolone
  • Bupivacaine
  • Placebo
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Where

1 site
M D Anderson Cancer Center
Houston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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