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Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?

RecruitingEARLY Phase 1Ages 18 Years - 85 YearsAllTexas Tech University Health Sciences Center, El …
NCT06016465 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Meet ICHD-3 Migraine Headache Criteria * Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2 * Nerve block performed with bupivacaine 0.5% Exclusion Criteria: * Head trauma * Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma) * Headache in the setting of viral syndrome * Chronically on steroids * Known allergy to dexamethasone * Unable to reach the patient by phone or text for follow-up * Gestational diabetes or other uncontrolled diabetes * Known to be immunocompromised
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What it tests

  • Dexamethasone Oral
  • Placebo
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Where

1 site
University Medical Center of El Paso
El Paso, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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