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FDG-PET in the Diagnosis of Autoimmune Encephalitis

Recruitingn/aAges any - anyAllUniversity of Milano Bicocca
NCT06019975 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this retrospective observational study is to compare brain fluorodeoxyglucose-positron emission tomography (FDG-PET) of patients with autoimmune encephalitis, normal controls and patients with Alzheimer's disease (AD). The main question it aims to answer is: •is there a specific pattern of brain metabolism in patients with autoimmune encephalitis Participants data and images will be retrospectively collected from hospital records, and FDG-PET images will be analyzed by means of statistical parametric mapping (SPM). Controls will be selected from validated public databases.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of autoimmune encephalitis according to clinical criteria * Brain magnetic resonance imaging performed between clinical presentation and treatment * Cerebrospinal fluid analysis performed between clinical presentation and treatment * Brain FDG-PET performed between clinical presentation and treatment * Autoantibodies testing performed between clinical presentation and treatment Exclusion Criteria: * Refusal to give consent for the study
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What it tests

  • FDG-PET
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Where

6 sites
Azienda Sanitaria Universitaria Friuli Centrale
Udine, Italy
IRCCS Ospedale Policlinico San Martino
Genoa, Italy
Fondazione IRCCS Mondino
Pavia, Italy
Fondazione IRCCS Istituto Neurologico "Carlo Besta"
Milan, Italy
Ospedale San Paolo
Milan, Italy
Fondazione IRCCS San Gerardo dei Tintori
Monza, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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