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Molecular Markes of Fibrosis of Endometriosis and Their Use in Predicting Disease Severity

Recruitingn/aAges 18 Years - 45 YearsFemaleGeneral University Hospital, Prague
NCT06020482 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The primary aim of the project is to analyse gene expression in individual types of ectopic endometrium (ovarian endometriosis, peritoneal endometriosis, deep infiltrating endometriosis) and compare it with gene expression in eutopic endometrium. The analysis focuses on the identification of genes with significantly increased expression in each type of ectopic endometrium and comparison of their expression with the degree of disease, ovarian reserve and clinical manifestations of the disease (pain, infertility).

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📋 Eligibility rules (as published)
Inclusion Criteria: * women (18-45 years) * signed informed consent with the study * absence of hormonal treatment 3 months before the planned procedure Inclusion criteria for group A: \- laparoscopically and histologically confirmed endometriosis dg. Inclusion criteria for group B: * patients without endometriosis * patients who are undergoing an elective laparoscopic or hysteroscopic procedure in our department for another benign indication * patients with excluded malignant disease Exclusion Criteria: * absence of informed consent * patients who do not meet the inclusion criteria during surgery * patient younger than 18 years of age or older than 45 years of age
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What it tests

  • Molecular markes of fibrosis of single types of endometriosis and their use in predicting disease severity
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Where

1 site
General University Hospital in Prague
Prague, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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