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Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women

RecruitingNAAges 45 Years - anyFemaleLinkoeping University
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In plain words

What the trial is, and whether it could suit you

The goal of this randomised controlled trial is to investigate the effects of and compare two modes of physical exercise (strength training and high-intensity aerobic exercise) to unchanged physical activity on vasomotor symptoms (hot flushes) in postmenopausal women. The main question it aims to answer is the effect of 15 weeks of strength training vs high intensity aerobic training vs unchanged physical activity on frequency and severity of hot flushes. Participants will be randomised to: 1. strength training 2. high-intensity aerobic training 3. untreated control group. Researchers will compare strength training, high-intensity aerobic training and untreated control group to see if training can reduce hot flushes.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Postmenopausal women (one of: ≥ 12 months since last menstruation; amenorrhea due to intrauterine device or hysterectomy and Follicle Stimulating Hormone (FSH) \>30 mIU/ml; bilateral oophorectomy; induced menopause due to chemotherapy or radiation and ≥2 years amenorrhea); * ≥ 28 moderate to severe hot flushes per week during a 2-week screening period, registered through a daily VMS diary; * Age ≥45 years; * Physical ability to participate in strength training or high intensity aerobic exercise for 60 minutes, 3 times/week during 15 weeks; * Understand Swedish orally and in writing Exclusion Criteria: * Regular physical activity \>30 minutes per week of vigorous intensity or ≥150 minutes of moderate intensity or combined activities representing maximum 150 minutes of moderate intensity; * Use of systemic menopausal hormone therapy the last 2 months; * Use of natural preparations such as herbal preparations for VMS, or other medications for VMS the last 2 months; * Capillary hemoglobin \<110 g/l; * Blood pressure \>160 mmHg systolic or \>100 mmHg diastolic; * Unstable medical condition with a potential to affect VMS (like unregulated thyroid disease); * Medical condition that by a physician is judged not appropriate (because of potential to affect VMS or risk of injury with vigorous exercise)
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What it tests

  • Strength training
  • High-intensity aerobic training
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Where

2 sites
Region Kalmar Län
Kalmar, Sweden
Region Östergötland
Linköping, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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