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An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL

RecruitingNAAges 18 Years - anyAllLondon Health Sciences Centre Research Institute …
NCT06032208 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Investigators know that many patients who are on dialysis suffer from burden of unwanted symptoms, which can affect quality of life. The understanding and treatment of symptom burden by healthcare providers is limited and should be recognized as a high priority in the care of the dialysis population. In this study, the investigators will be assessing symptom burden using the London Evaluation of Illness "LEVIL," an application based platform where patients self-report their symptoms with one to three hemodialysis treatments per week for 28 weeks. The investigators would like to compare the currently available dialyzer with a new dialyzer that is capable of removing solutes of higher molecular weight that may or may not cause patients to experience symptoms related to increased amounts of toxins in their blood.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Conventional thrice weekly HD schedule * Must be on chronic hemodialysis for at least 3 months * Age ≥18 years * Willing and able to give informed consent Exclusion Criteria: * Active infection (may enroll once infection is cleared) * Patients receiving daily hemodialysis treatment * Patients currently receiving Hemodiafiltration (HDF), Hemofiltration (HF) or Isolated ultrafiltration (ISO UF) more than once in three months * Visual impairment * History of neurocognitive impairment * History of stroke (CVA)
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What it tests

  • Theranova Dialyzer
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Where

4 sites
Seven Oaks Hospital Chronic Disease Innovation Centre Inc. (CDIC)
Winnipeg, Canada
QEII Health Sciences Centre, Nova Scotia Health
Halifax, Canada
Victoria Hospital, London Health Sciences Centre
London, Canada
Westmount Kidney Care Centre
London, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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