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Using Urine Samples to Identify Lung Cancer

Recruitingn/aAges 18 Years - 90 YearsAllMemorial Sloan Kettering Cancer Center
NCT06033248 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The researchers are doing this study to test the ability of an animal biosensor platform (ABP) to detect NSCLC. Participants in this study will either be diagnosed with NSCLC, suspected to have NSCLC, or have not been diagnosed or suspected to have NSCLC. The ABP test uses laboratory animals that are trained to detect (by smell) different chemicals in urine. Studies show that people with lung cancer have unique chemicals in their urine that are not present in people without lung cancer, and researchers think these chemicals can be used to identify people with lung cancer without the need for invasive procedures (like biopsy).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Phase I (with NSCLC): Aged 18 to 90 years with histologically proven, previously untreated stage I, II, or IIIA NSCLC °Note: Single, monolateral nodule of at least 50% solid composition visible on a Chest CT scan that is suspicious for a primary neoplasm as confirmed by an official MSK radiologist read * Phase I (without NSCLC): Aged 18 to 90 years with patient confirmed absence of NSCLC * Phase II: Aged 18 to 90 years with suspected but undiagnosed stage I, II, or IIIA NSCLC by CT and/or PET scan criteria Exclusion Criteria: * Aged \<18 years * Lack of available results from low-dose CT * Receipt of radiation, chemotherapy, biological therapy, resection, or any other treatment for any cancer in the previous year * Pregnant (for women) * Taking drugs that affect the immune system * Chronic disease related to the immune system * Missing clinical data (i.e., current clinical staging)
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What it tests

  • urine sample
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Where

7 sites
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge, United States
Memorial Sloan Kettering Monmouth (All Protocol Activities)
Middletown, United States
Memorial Sloan Kettering Bergen (All Protocol Activities)
Montvale, United States
Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities)
Commack, United States
Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, United States
Memorial Sloan Kettering Nassau (All Protocol Activities)
Uniondale, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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