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The Effect of Exercise Training and Detraining on Frailty and Fall Risk in Patients With Chronic Heart Failure

RecruitingNAAges 18 Years - 100 YearsAllAristotle University Of Thessaloniki
NCT06036615 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chronic Heart Failure (CHF) is the endpoint for some cardiac and respiratory conditions as well as ageing affecting 1-2% of the global adult population. CHF requires a costly treatment, frequent hospitalizations due its severe complications leading CHF eventually to a frequent cause of morbidity and mortality worldwide. Another common complication of CHF is frailty. Frailty is a complex clinical syndrome associated with CHF, resulting from multiple organ impairment; physiological reserves decrease and vulnerability to stressors increase. Up to 79% of PwCHF are frail leading to reduced functional capacity, quality of life (QoL), and psychological well-being in CHF, and it is an independent predictor of mortality in cardiovascular disease. The role of cardiac rehabilitation (CR) programs for PwCHF in preventing frailty has recently draw the attention of the scientific world. Exercise cons

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age \> 18 yrs. of either gender * Confirmed diagnosis (by echocardiography) of HF reduced or preserved left ventricular ejection fraction (HFrEF/ΗFpEF) * Symptomatic New York Heart Association (NYHA) class II-III Exclusion Criteria: * Acute Myocardial Infarction (\<4 weeks) * Severe valvular diseases * Potentially malignant arrhythmias * Νeurological, or orthopedic limitations/non- ambulant status * Cognitive disorders * Poor regulation of comorbidities * Already participating in organized exercise programs * Current pregnancy * NYHA function class IV * Inability/unwillingness to give informed consent
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What it tests

  • Exercise Intervention
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Where

1 site
Sports Medicine Laboratory, Aristotle University of Thessaloniki
Thessaloniki, Greece
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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