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โ† Trials
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Functional Magnetic Resonance-Based Observations of Brain Networks in Moyamoya Disease Patients Under Anesthesia

Recruitingn/aAges 18 Years - 65 YearsAllBeijing Tiantan Hospital
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In plain words

What the trial is, and whether it could suit you

Moyamoya disease is characterized by progressive stenosis of the genesis of the distal internal carotid arteries bilaterally and progressive generation of compensatory pathological vascular networks at the basis cranii, and these pathological vasculature has poor vascular reactivity. Perioperative circulatory management of patients with smoky vessels to ensure perfusion of brain tissue and integrity of brain network during surgery to minimize postoperative impairment of neurological functions, including motor, sensory, emotional and cognitive functions, is the key point of perioperative circulatory management of moyamoya disease. Functional Magnetic Resonance Imaging (fMRI) has been routinely used in various cerebrovascular diseases to further evaluate cerebrovascular reserve and cerebral network connectivity. The purpose of this study is to observe the changes in cerebral blood flow, ce

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients with moyamoya disease scheduled for direct or indirect intracranial and extracranial revascularization surgery * Age between 18-65 years * Obtain written informed consent. Exclusion Criteria: * Patients with preoperative claustrophobia, sensory or motor aphasia that are unable to understand and cooperate with the examination * Preoperative cranial imaging suggesting cerebral infarction lesion diameter \>15mm * Patients allergic to anesthetic drugs * Metal implants in the body * Undergoing other experimental drug or instrumentation trials
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What it tests

  • Not listed
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Where

1 site
Beijing Tiantan Hospital, Capital Medical University
Beijing, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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